Dr. Xiaolong Yang has received $743,000 for a 5-year research grant from CIHR (Canadian Institute of Health Research) to study the roles of a novel Hippo signaling pathway in lung cancer. 2012 January 30
Lung cancer is the most common cancer worldwide, killing 1.2 million
people annually. Therefore, identification of genes responsible for
lung cancer development is crucial for its successful therapies. Dr.
Yang's lab has recently discovered TAZ, a major component of an
emerging Hippo signaling pathway, as a novel gene causing lung cancer.
In this research project, Dr. Yang will further explore how TAZ and
other components of the Hippo signaling pathway contribute to lung
cancer development and progression using human lung cancer cell lines,
mouse model, and clinical cancer patient tissues. The research
findings from this research project will finally identified a new
pathway critical for lung cancer development and will have great
implications for the future diagnosis and therapy of lung cancer.
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